Martin-Luther-Universität Halle-Wittenberg

Plant Nutrition 2019

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Dr. Minh Hoang

Minh Hoang

Minh Hoang

Minh Hoang

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Minh Hoang
Postdoc (wissenschaftlicher Mitarbeiterin)

Martin-Luther-Universität
Halle-Wittenberg
Betty-Heimann-Straße 3
Raum 1.27.0
06120 Halle (Saale)

Telefon: 0345 55 22423
Telefax: 0345 55 27113

Research

During my undergraduate and graduate studies in Vietnam, I worked on multiple projects involving the extraction of secondary metabolites from callus, hairy roots, and hydroponic roots, and the evaluation of their biological activities. My PhD project in Montpellier (France) focused on the process of iron (Fe) transport during seed development. During my PhD, I was first involved in a project focusing on the biochemical dissection of Fe transport into the embryo of Arabidopsis. In this study, I demonstrated biochemically and genetically the direct role of ascorbate, which is released from the embryos, as the molecule responsible for the Fe reduction step that occurs prior to Fe uptake at the embryo surface. I have then successfully set up a yeast complementation approach to isolate potential ascorbate efflux transporters. During this screening, I have identified the first vacuolar efflux transporter for ascorbate in plants. This transporter belongs to the multidrug and toxic efflux (MATE) family. Importantly, I demonstrated that this transporter is crucial to remobilize Fe from vacuoles during germination and growth of Arabidopsis seedlings in Fe deficiency. Another identified protein may contribute to the transport and remobilization of iron from apoplastic Fe pools in roots. After my PhD, I returned to Vietnam for two years and focused on the isolation, screening and characterization of plant growth-promoting rhizobacteria which enhance salt tolerance of plant.

I joined the the Peiter lab in 2018 to work again on cation transport in plants, moving from Fe to calcium (Ca) and manganese (Mn). The transport and homeostasis of both Ca and Mn is central to chloroplast functioning and the integration of the chloroplast in the cellular signalling network. Recently, proteins of the BICAT family that are related to GDT1, a Ca and Mn transporter in yeast, have been described to transport both cations, and to determine the generation of Ca signals, in the chloroplast. So far, these functions have only been examined in the model plant Arabidopsis, and even there, the function of those novel transporters is still obscure. Therefore, my project, which is part of the Agripoly-DPP graduate school, aims to elucidate the role of these proteins in determining Ca- and Mn-related chloroplast functions in two crops, sugar beet and barley, that are phylogenetically distant from Arabidopsis. Furthermore, we aim to better understand how chloroplastic Ca signals are formed in Arabidopsis and what role BICATs play in this process.

Publications

Alejandro S, Meier B, Hoang MTT, Peiter E (2023). Cation Diffusion Facilitators of Beta vulgaris reveal diversity of metal handling in dicotyledons. Plant, Cell and Environment 46, 1629-1652.

Hoang MTT, Almeida D, Chay S, Alcon C, Corratge-Faillie C, Curie C, Mari S (2021). AtDTX25, a member of the multidrug and toxic compound extrusion family, is a vacuolar ascorbate transporter that controls intracellular iron cycling in Arabidopsis. New Phytologist 231, 1956-1967.

He J, Rössner N, Hoang MTT, Alejandro S, Peiter E (2021). Transport, functions, and interactions of calcium and manganese in plant organellar  compartments. Plant Physiology 187, 1940-1972.

Cao DM, Vu PTB, Hoang MTT, Bui AL, Quach PND (2020). Developing a sufficient protocol for the enhancement of α-glucosidase inhibitory activity by Urena lobata L. aeroponic hairy roots using exogenous factors, a precursor, and an elicitor. Plants 9, 548.

Chu TN, Bui VL, Hoang MTT (2020). Pseudomonas PS01 isolated from maize rhizosphere alters root system architecture and promotes plant growth. Microorganisms 8, 471.

Chu TN, Tran BTH, Bui VL, Hoang MTT (2019). Plant growth-promoting rhizobacterium Pseudomonas PS01 induces salt tolerance in Arabidopsis thaliana. BMC Research Notes, 12, 1–7.

Frank J, Happeck R, Meier B, Hoang MTT, Stribny J, Hause G, Ding H, Morsomme P, Baginsky, Peiter E (2019). Chloroplast-localized BICAT proteins shape stromal calcium signals and are required for efficient photosynthesis. New Phytologist, 221, 866–880.

Grillet L, Ouerdane L, Flis P, Hoang MTT, Isaure MP, Lobinski R, Curie C, Mari S (2014). Ascorbate efflux as a new strategy for iron reduction and transport in plants. Journal of Biological Chemistry 289, 2515–2525.

CV

Since 2018Postdoctoral Research Fellow, Plant Nutrition Laboratory, MLU Halle-Wittenberg
2016-2017Lecturer, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam
2012-2015PhD (Integrative Biology of Plants), Montpellier SupAgro (Ecole Nationale Supérieure d'Agronomie), France
2009-2011Master (Biochemistry), University of Science, Vietnam National University, Ho Chi Minh City, Vietnam
2005-2009Bachelor (Biotechnology), University of Science, Vietnam National University, Ho Chi Minh City, Vietnam

Awards

2012PhD Scholarship “Viet Nam oversea scholarship program for agricultural biotechnology and aquiculture”

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